Is Route 53 an origin for cloud front?

When you create a CloudFront distribution that point for example, to a S3 bucket, CloudFront by default create a domain name, such as [distribution].cloudfront.com. You can after use Amazon Route 53 to create an alias record that points to your CloudFront distribution.

You can find more information here : https://docs.aws.amazon.com/Route53/latest/DeveloperGuide/routing-to-cloudfront-distribution.html